Helena BianchiDiet, Functional Medicine, Longevity

When discussing bone health, three often underrated nutrients—Vitamin K2, boron, and collagen—play crucial roles that are frequently overlooked.

Vitamin K2

  • Calcium Regulation: Activates proteins that help bind calcium to the bone matrix, strengthening bones and improving bone mineral density.
  • Calcium Deposition: Regulates calcium deposition, ensuring calcium is directed to bones and teeth rather than accumulating in arteries.
  • Reduced Fracture Risk: Adequate intake can reduce the risk of fractures, particularly in postmenopausal women at higher risk for osteoporosis.
  • Bone Mineral Density: Several studies have shown vitamin K2 supplementation can increase Bone Mineral Density, particularly in the lumbar spine and hip
  • PubMed References: PMC7645307, PMC15771560, PMC29480629

Boron

  • Bone Growth and Maintenance: Boron is essential for the growth and maintenance of bone tissue. It influences the production and activity of steroid hormones, which are crucial for bone health. Boron supplementation has been shown to markedly reduce urinary excretion of calcium and magnesium, which are critical minerals for bone health. By reducing the loss of these minerals, boron helps maintain bone density and strength.
  • Vitamin D Metabolism: Helps extend the half-life of vitamin D, which is crucial for calcium absorption and bone maintenance. Supplementation with boron has been shown to stimulate bone growth in vitamin D-deficient animals and alleviate dysfunctions in mineral metabolism characteristic of vitamin D deficiency
  • Estrogen Metabolism: Boron influences the metabolism of estrogen, a hormone vital for bone health, particularly in postmenopausal women. It helps extend the half-life of estrogen, thereby enhancing its beneficial effects on bone strength and reducing the risk of osteoporosis.
  • PubMed References: PMC4712861, PMC32540741, PMC7889887

Collagen

  • Structural Integrity: Constitutes a significant part of the bone matrix, providing structural integrity and flexibility. It interacts with minerals like calcium to form a strong and resilient bone structure
  • Bone Turnover Markers and Bone Mineral Density: Research indicates that collagen supplementation improves bone turnover markers, which are indicators of bone formation and resorption. In particular, collagen peptides have been shown to reduce the excretion of bone collagen breakdown products, indicating a reduction in bone loss and an increase in bone formation. Daily intake of collagen peptides can help increase bone mineral density.
  • PubMed References: PMC5793325, PMC34520654, PMC29337906

By incorporating these often-overlooked nutrients into your diet, you can build a stronger, healthier foundation for your bones, ensuring long-term resilience and vitality.

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